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Article

Template boundary definition in mammalian telomerase.

Genes & development - 15 Nov 2003

Chen Jiunn-Liang, Greider Carol W

Abstract excerpt

Telomerase uses a short template sequence in its intrinsic RNA component to synthesize telomere repeats. Disruption of the helix P1b in human telomerase RNA or alteration of its distance from the template resulted in telomerase copying residues past the normal template boundary both in vivo and in vitro. Therefore, helix P1b is important for template boundary definition in human telomerase. Mouse telomerase RNA...

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Identifiers

PMID: 14630939
DOI: 10.1101/gad.1140303
PMCID: PMC280623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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