Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studies

24 Aug 2005

Abstract excerpt

BACKGROUND: Signal transducers and activators of transcription (STATs) play a critical role in antiviral defence. STAT3 is also important in cell protection against inflammatory damage. STAT proteins are activated by interferons and by hepatoprotective cytokines of the interleukin 6 superfamily, including cardiotrophin 1. METHODS: We analysed the status of STATs in hepatitis C virus (HCV) infected livers and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Hepatitis C virus research
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16120756
DOI: 10.1136/gut.2005.070060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studiesPMID 16120756Read ↗

Pegylated IFN-α regulates hepatic gene expression through transient Jak/STAT activationSemantic proximity Read ↗

Hepatic SOCS3 expression is strongly associated with non-response to therapy and race in HCV and HCV/HIV infection.Semantic proximity Read ↗

Hepatitis C Virus Infection Impairs IRF-7 Translocation and Alpha Interferon Synthesis in Immortalized Human HepatocytesSemantic proximity Read ↗

Signal Transducer and Activator of Transcription 4 in Liver DiseasesSemantic proximity Read ↗

Hepatitis C Virus-Mediated Enhancement of MicroRNA miR-373 Impairs the JAK/STAT Signaling PathwaySemantic proximity Read ↗

Ups and downs: The STAT1:STAT3 seesaw of Interferon and gp130 receptor signallingSemantic proximity Read ↗

STAT proteins – Key regulators of anti-viral responses, inflammation, and tumorigenesis in the liverSemantic proximity Read ↗

STAT1 is essential for the inhibition of hepatitis C virus replication by interferon-λ but not by interferon-αSemantic proximity Read ↗

Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway.Semantic proximity Read ↗

Microarray analyses and molecular profiling of Stat3 signaling pathway induced by hepatitis C virus core protein in human hepatocytesSemantic proximity Read ↗

Toll-like receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells.Semantic proximity Read ↗

Interferon signaling and treatment outcome in chronic hepatitis C.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.