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Article

Evaluation of Nyholt's procedure for multiple testing correction.

Human heredity - 1 Jan 2005

Salyakina Daria, Seaman Shaun R, Browning Brian L, Dudbridge Frank, Muller-Myhsok Bertram

Abstract excerpt

OBJECTIVE: A simple method for accounting efficiently for multiple testing of many SNPs in an association study was recently proposed by Nyholt, but its performance was not extensively evaluated. The method involves estimating an 'effective number' of independent tests and then adjusting the smallest observed p value using Sidák's formula based on this number of tests. We sought to carry out an empirical and...

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PMID: 16118503
DOI: 10.1159/000087540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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