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Article

A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other.

American journal of human genetics - 1 Apr 2004

Nyholt Dale R

Abstract excerpt

In this report, we describe a simple correction for multiple testing of single-nucleotide polymorphisms (SNPs) in linkage disequilibrium (LD) with each other, on the basis of the spectral decomposition (SpD) of matrices of pairwise LD between SNPs. This method provides a useful alternative to more computationally intensive permutation tests. A user-friendly interface (SNPSpD) for performing this correction is...

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Identifiers

PMID: 14997420
DOI: 10.1086/383251
PMCID: PMC1181954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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