Article
The PscE-PscF-PscG complex controls type III secretion needle biogenesis in Pseudomonas aeruginosa.
The Journal of biological chemistry - 28 Oct 2005
Quinaud Manuelle, Chabert Jacqueline, Faudry Eric, Neumann Emmanuelle, Lemaire David, Pastor Alexandrine, Elsen Sylvie, Dessen Andréa, Attree Ina
Abstract excerpt
Type III secretion (T3S) systems play key roles in pathogenicity of many Gram-negative bacteria and are employed to inject toxins directly into the cytoplasm of target cells. They are composed of over 20 different proteins that associate into a basal structure that traverses both inner and outer bacterial membranes and a hollow, needle-like structure through which toxins travel. The PscF protein is the main...
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