Article
Modified needle-tip PcrV proteins reveal distinct phenotypes relevant to the control of type III secretion and intoxication by Pseudomonas aeruginosa.
PloS one - 29 Mar 2011
Sato Hiromi, Hunt Meredith L, Weiner Joshua J, Hansen Andrew T, Frank Dara W
Abstract excerpt
The type III secretion system (T3SS) is employed to deliver effector proteins to the cytosol of eukaryotic hosts by multiple species of Gram-negative bacteria, including Pseudomonas aeruginosa. Translocation of effectors is dependent on the proteins encoded by the pcrGVHpopBD operon. These proteins form a T3S translocator complex, composed of a needle-tip complex (PcrV), translocons (PopB and PopD), and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
