Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Control of type III secretion activity and substrate specificity by the cytoplasmic regulator PcrG.

Proceedings of the National Academy of Sciences of the United States of America - 13 May 2014

Lee Pei-Chung, Zmina Stephanie Elizabeth, Stopford Charles Morgan, Toska Jonida, Rietsch Arne

Abstract excerpt

Pathogenic Gram-negative bacteria use syringe-like type III secretion systems (T3SS) to inject effector proteins directly into targeted host cells. Effector secretion is triggered by host cell contact, and before contact is prevented by a set of conserved regulators. How these regulators interface with the T3SS apparatus to control secretion is unclear. We present evidence that the proton motive force (pmf)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Bacterial Secretion Systems

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytoplasm

Share to Gene Expression Regulation, Bacterial

Share to Protein Structure, Tertiary

Share to Proton-Motive Force

Share to Pseudomonas aeruginosa

Share to Substrate Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 24778208
DOI: 10.1073/pnas.1402658111
PMCID: PMC4024851

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Control of type III secretion activity and substrate specificity by the cytoplasmic regulator PcrG.PMID 24778208Read ↗

Regulation of the Yersinia type III secretion system: traffic control.Semantic proximity Read ↗

The PscE-PscF-PscG complex controls type III secretion needle biogenesis in Pseudomonas aeruginosa.Semantic proximity Read ↗

Tetratricopeptide repeats are essential for PcrH chaperone function in Pseudomonas aeruginosa type III secretion.Semantic proximity Read ↗

PcrH of Pseudomonas aeruginosa is essential for secretion and assembly of the type III translocon.Semantic proximity Read ↗

Modified needle-tip PcrV proteins reveal distinct phenotypes relevant to the control of type III secretion and intoxication by Pseudomonas aeruginosa.Semantic proximity Read ↗

Fueling type III secretion.Semantic proximity Read ↗

A Structure-Function-Inhibition Analysis of the Pseudomonas aeruginosa Type III Secretion Needle Protein PscF.Semantic proximity Read ↗

MxiA, MxiC and IpaD Regulate Substrate Selection and Secretion Mode in the T3SS of Shigella flexneri.Semantic proximity Read ↗

A type III secretion system inhibitor targets YopD while revealing differential regulation of secretion in calcium-blind mutants of Yersinia pestis.Semantic proximity Read ↗

YscP and YscU regulate substrate specificity of the Yersinia type III secretion system.Semantic proximity Read ↗

Protein Export via the Type III Secretion System of the Bacterial FlagellumSemantic proximity Read ↗

Functional characterization of the type III secretion ATPase HrcN from the plant pathogen Xanthomonas campestris pv. vesicatoria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.