Article
A protein secreted by the Salmonella type III secretion system controls needle filament assembly.
eLife - 17 Jul 2018
Kato Junya, Dey Supratim, Soto Jose E, Butan Carmen, Wilkinson Mason C, De Guzman Roberto N, Galan Jorge E
Abstract excerpt
Type III protein secretion systems (T3SS) are encoded by several pathogenic or symbiotic bacteria. The central component of this nanomachine is the needle complex. Here we show in a Salmonella Typhimurium T3SS that assembly of the needle filament of this structure requires OrgC, a protein encoded within the T3SS gene cluster. Absence of OrgC results in significantly reduced number of needle substructures but does...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.