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Article

Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma.

Human molecular genetics - 1 Oct 2005

Matsuda Akira, Hirota Tomomitsu, Akahoshi Mitsuteru, Shimizu Makiko, Tamari Mayumi, Miyatake Akihiko, Takahashi Atsushi, Nakashima Kazuko, Takahashi Naomi, Obara Kazuhiko, Yuyama Noriko, Doi Satoru, Kamogawa Yumiko, Enomoto Tadao, Ohshima Koichi, Tsunoda Tatsuhiko, Miyatake Shoichiro, Fujita Kimie, Kusakabe Moriaki, Izuhara Kenji, Nakamura Yusuke, Hopkin Julian, Shirakawa Taro

Abstract excerpt

The extracellular matrix glycoprotein tenascin-C (TNC) has been accepted as a valuable histopathological subepithelial marker for evaluating the severity of asthmatic disease and the therapeutic response to drugs. We found an association between an adult asthma and an SNP encoding TNC fibronectin type III-D (Fn-III-D) domain in a case-control study between a Japanese population including 446 adult asthmatic...

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PMID: 16115819
DOI: 10.1093/hmg/ddi311

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TNC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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