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Article

Acid-labile subunit deficiency: phenotypic similarities and differences between human and mouse.

Journal of endocrinological investigation - 1 Jan 2005

Domené H M, Bengolea S V, Jasper H G, Boisclair Y R

Abstract excerpt

IGF-I and IGF-II (IGFs) form higher molecular weight complexes with specific binding proteins (IGFBP-1 to -6). These complexes are referred to as binary complexes consisting of IGF-I or IGF-II and one IGFBP, or as ternary complexes each consisting of either of IGF-I or IGF-II, IGFBP-3 or -5, and an acid-labile subunit known as ALS. Ternary complex formation restricts the IGFs to the circulation and prolongs their...

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Identifiers

PMID: 16114275

Genes

IGFALS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Acid-labile subunit deficiency: phenotypic similarities and differences between human and mouse.PMID 16114275Read ↗

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