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Article

Incomplete activation of macrophage apoptosis during intracellular replication of Legionella pneumophila.

Infection and immunity - 1 Sept 2005

Abu-Zant Alaeddin, Santic Marina, Molmeret Maelle, Jones Snake, Helbig Jürgen, Abu Kwaik Yousef

Abstract excerpt

The ability of the intracellular bacterium Legionella pneumophila to cause disease is totally dependent on its ability to modulate the biogenesis of its phagosome and to replicate within alveolar cells. Upon invasion, L. pneumophila activates caspase-3 in macrophages, monocytes, and alveolar epit...

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Identifiers

PMID: 16113249
DOI: 10.1128/IAI.73.9.5339-5349.2005
PMCID: PMC1231138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16113249-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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