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Article

Legionella pneumophila inhibits macrophage apoptosis by targeting pro-death members of the Bcl2 protein family.

Proceedings of the National Academy of Sciences of the United States of America - 20 Mar 2007

Banga Simran, Gao Ping, Shen Xihui, Fiscus Valena, Zong Wei-Xing, Chen Lingling, Luo Zhao-Qing

Abstract excerpt

To establish a vacuole that supports bacterial replication, Legionella pneumophila translocates a large number of bacterial proteins into host cells via the Dot/Icm type IV secretion system. Functions of most of these translocated proteins are unknown, but recent investigations suggest their roles in modulating diverse host processes such as vesicle trafficking, autophagy, ubiquitination, and apoptosis. Cells...

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PMID: 17360363
DOI: 10.1073/pnas.0611030104
PMCID: PMC1829273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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