A Caspase-Independent Pathway Mediates Macrophage Cell Death in Response to<i>Mycobacterium tuberculosis</i>Infection

Abstract excerpt

Macrophages can undergo apoptosis after infection with Mycobacterium tuberculosis. This macrophage response deprives the bacillus of its niche cell and supports the host response through better antigen presentation. The intracellular pathways of apoptosis that elaborate this macrophage response are not well understood. To address this issue, we investigated the contribution of various apoptosis pathways to M....

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