Article
The mechanism of killing and exiting the protozoan host Acanthamoeba polyphaga by Legionella pneumophila.
Environmental microbiology - 1 Feb 2000
Gao L Y, Kwaik Y A
Abstract excerpt
The ability of Legionella pneumophila to cause legionnaires' disease is dependent on its capacity to replicate within cells in the alveolar spaces. The bacteria kill mammalian cells in two phases: induction of apoptosis during the early stages of infection, followed by an independent and rapid ne...
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