Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tonsillar homing of Epstein-Barr virus-specific CD8+ T cells and the virus-host balance.

The Journal of clinical investigation - 1 Sept 2005

Hislop Andrew D, Kuo Michael, Drake-Lee Adrian B, Akbar Arne N, Bergler Wolfgang, Hammerschmitt Nicolas, Khan Naeem, Palendira Umaimainthan, Leese Alison M, Timms Judith M, Bell Andrew I, Buckley Christopher D, Rickinson Alan B

Abstract excerpt

Patients with infectious mononucleosis (IM) undergoing primary EBV infection show large expansions of EBV-specific CD8+ T cells in the blood. While latent infection of the B cell pool is quickly controlled, virus shedding from lytically infected cells in the oropharynx remains high for several mo...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Carrier State

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to Herpesvirus 4, Human

Share to Palatine Tonsil

Share to Receptors, CCR7

Share to Receptors, Chemokine

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 16110323
DOI: 10.1172/JCI24810
PMCID: PMC1187932

Genes

CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16110323-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tonsillar homing of Epstein-Barr virus-specific CD8+ T cells and the virus-host balance.PMID 16110323Read ↗

EBV-infected B cells in infectious mononucleosis: viral strategies for spreading in the B cell compartment and establishing latency.Semantic proximity Read ↗

The spatial landscape of infectious mononucleosis tonsilsSemantic proximity Read ↗

A tonsil organoid model reveals Epstein-Barr virus infected germinal center B cell states during primary infectionSemantic proximity Read ↗

Compartmentalization of Total and Virus-Specific Tissue-Resident Memory CD8+ T Cells in Human Lymphoid OrgansSemantic proximity Read ↗

Epstein-Barr virus-infected tonsillar marginal zone B cells in vivo as a precursor for immunosuppression-related B-cell lymphomaSemantic proximity Read ↗

IL-21 signaling promotes the establishment of KSHV infection in human tonsil lymphocytes by increasing early targeting of plasma cellsSemantic proximity Read ↗

Epstein-Barr Virus Infection of Langerhans Cell Precursors as a Mechanism of Oral Epithelial Entry, Persistence, and ReactivationSemantic proximity Read ↗

Epstein-Barr virus colonization of tonsillar and peripheral blood B-cell subsets in primary infection and persistenceSemantic proximity Read ↗

Proteome-wide analysis of CD8+ T cell responses to EBV reveals differences between primary and persistent infectionSemantic proximity Read ↗

MHC II tetramers visualize human CD4+ T cell responses to Epstein-Barr virus infection and demonstrate atypical kinetics of the nuclear antigen EBNA1 response.Semantic proximity Read ↗

Primary B Lymphocytes Infected with Kaposi's Sarcoma-Associated Herpesvirus Can Be Expanded In Vitro and Are Recognized by LANA-Specific CD4+ T Cells.Semantic proximity Read ↗

Tonsillar memory B cells, latently infected with Epstein–Barr virus, express the restricted pattern of latent genes previously found only in Epstein–Barr virus-associated tumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.