Article
Epstein-Barr virus colonization of tonsillar and peripheral blood B-cell subsets in primary infection and persistence
8 Apr 2009
Abstract excerpt
Epstein-Barr virus (EBV) persists in the immune host by preferentially colonizing the isotype-switched (IgD(-)CD27(+)) memory B-cell pool. In one scenario, this is achieved through virus infection of naive (IgD(+)CD27(-)) B cells and their differentiation into memory via germinal center (GC) transit; in another, EBV avoids GC transit and infects memory B cells directly. We report 2 findings consistent with this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
