Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Modifiers of Hemoglobin Expression from a Clinical Perspective in Hemoglobinopathy Patients with Beta Thalassemia and Sickle Cell Disease

5 Nov 2024

Abstract excerpt

Hemoglobinopathies, namely β-thalassemia and sickle cell disease (SCD), are hereditary diseases, characterized by molecular genetic aberrations in the beta chains of hemoglobin. These defects affect the normal production of hemoglobin with severe anemia due to less or no amount of beta globins in patients with β-thalassemia (quantitative disorder), while SCD is a serious disease in which a mutated form of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Hemoglobinopathies and Related Disorders
Share to Iron Metabolism and Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39595957
DOI: 10.3390/ijms252211886

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Modifiers of Hemoglobin Expression from a Clinical Perspective in Hemoglobinopathy Patients with Beta Thalassemia and Sickle Cell DiseasePMID 39595957Read ↗

Recent Approaches for Manipulating Globin Gene Expression in Treating HemoglobinopathiesSemantic proximity Read ↗

A Small Key for a Heavy Door: Genetic Therapies for the Treatment of HemoglobinopathiesSemantic proximity Read ↗

Dissecting the role of genetic modifiers of hemoglobinopathies: A futuristic approach towards precision medicineSemantic proximity Read ↗

Fetal hemoglobin regulation in β-thalassemia: heterogeneity, modifiers and therapeutic approachesSemantic proximity Read ↗

Molecular basis of β thalassemia and potential therapeutic targets.Semantic proximity Read ↗

Disorders of Hemoglobin: Genetics, Pathophysiology, and Clinical ManagementSemantic proximity Read ↗

Genetic Basis and Genetic Modifiers of β-Thalassemia and Sickle Cell Disease.Semantic proximity Read ↗

β-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapies.Semantic proximity Read ↗

Significance of genetic modifiers of hemoglobinopathies leading towards precision medicine.Semantic proximity Read ↗

Thalassemias: from gene to therapy.Semantic proximity Read ↗

Modifier genes in Mendelian disorders: the example of hemoglobin disorders.Semantic proximity Read ↗

Genetic association studies in β-hemoglobinopathiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.