Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype.

Abstract excerpt

Gastric cancer (GC), one of the most common human cancers, can be classified into gastric or intestinal phenotype according to mucin expression. TP53 mutation, allelic deletion of the APC gene and nuclear staining of β-catenin are frequently detected in the intestinal phenotype of GC, whereas CDH1 gene mutation, microsatellite instability and DNA hypermethylation of MLH1 are common events in the gastric phenotype...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CAST gene
• Share to CDH1 gene
• Share to CDX2 gene