Article
[Relationship between the polymorphism of carboxylic esterases and genetic susceptibility to organophosphates pesticides exposure].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases - 1 Apr 2005
Zheng Jie, Zhou Zhi-jun, Zheng Guang, Dai Xu-feng, Gu Xi-an
Abstract excerpt
OBJECTIVE: To study the relationship between the polymorphism of butyrylcholinesterase (BChE, EC 3.1.1.8) and paraoxonase (PonE, EC 3.1.8.1), and the individuals' genetic susceptibility to organophosphates pesticides (OPs) exposure. METHODS: 75 OPs exposure workers were selected to determine their BChE-K, PON-192 and PON-55 genotypes using PCR-RFLP. The accumulative symptom scores and the whole blood...
Topics
- Adult
- Aryldialkylphosphatase
- Butyrylcholinesterase
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Occupational Exposure
- Organophosphorus Compounds
- Pesticides
- Polymerase Chain Reaction