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Article

Promoter polymorphisms in the nitric oxide synthase 3 gene are associated with ischemic stroke susceptibility in young black women.

Stroke - 1 Sept 2005

Howard Timothy D, Giles Wayne H, Xu Jianfeng, Wozniak Marcella A, Malarcher Ann M, Lange Leslie A, Macko Richard F, Basehore Monica J, Meyers Deborah A, Cole John W, Kittner Steven J

Abstract excerpt

BACKGROUND AND PURPOSE: Endothelial nitric oxide exerts a variety of protective effects on endothelial cells and blood vessels, and therefore the nitric oxide synthase 3 gene (NOS3) is a logical candidate gene for stroke susceptibility. METHODS: We used the population-based Stroke Prevention in Young Women case-control study to assess the association of five NOS3 polymorphisms in 110 cases (46% black) with...

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Identifiers

PMID: 16100023
DOI: 10.1161/01.STR.0000177978.97428.53
PMCID: PMC1494105

Genes

NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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