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Article

NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study.

Pharmacogenetics and genomics - 1 Dec 2006

Lee Craig R, North Kari E, Bray Molly S, Avery Christy L, Mosher Mary Jane, Couper David J, Coresh Josef, Folsom Aaron R, Boerwinkle Eric, Heiss Gerardo, Zeldin Darryl C

Abstract excerpt

OBJECTIVE: Endothelial nitric oxide synthase (NOS3) activity and cigarette smoking significantly influence endothelial function. We sought to determine whether cigarette smoking modified the association between NOS3 polymorphisms and risk of coronary heart disease or stroke. METHODS: All 1085 incident coronary heart disease cases, all 300 incident ischemic stroke cases, and 1065 reference individuals from the...

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Source

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Identifiers

PMID: 17108813
DOI: 10.1097/01.fpc.0000236324.96056.16
PMCID: PMC1978174

Genes

NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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