Article
Hepatitis B virus (HBV) genotypes/subgenotypes in China: mutations in core promoter and precore/core and their clinical implications.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jun 2007
Yuan Jing, Zhou Boping, Tanaka Yasuhito, Kurbanov Fuat, Orito Etsuro, Gong Zuojiong, Xu Liumei, Lu Jian, Jiang Xiaoling, Lai Weizhen, Mizokami Masashi
Abstract excerpt
BACKGROUND: The association of hepatitis B virus (HBV) genotypes with clinical course of infection is increasingly recognized. OBJECTIVES: In order to investigate the genetic diversity of HBV and its clinical implications, 241 HBV-infected patients including 34 with hepatocellular carcinoma (HCC) were enrolled in this study. METHODS: HBV genotyping was performed with an ELISA assay. HBV subgenotypes were...
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