Article
Specific mutations of basal core promoter are associated with chronic liver disease in hepatitis B virus subgenotype D1 prevalent in Turkey.
Microbiology and immunology - 1 Feb 2013
Sunbul Mustafa, Sugiyama Masaya, Kurbanov Fuat, Leblebicioglu Hakan, Khan Anis, Elkady Abeer, Tanaka Yasuhito, Mizokami Masashi
Abstract excerpt
The role of hepatitis B virus (HBV) genetics in the clinical manifestations of infection is being increasingly recognized. Genotype D is one of eight currently recognized major HBV genotypes. The virus is ubiquitous worldwide, but shows different features in different regions. One hundred and ninety-eight patients with chronic HBV infection were enrolled in this study, 38 of whom had been diagnosed with cirrhosis...
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