[Significance of the double mutations of C1673T/C1799G in HBV C promoter].

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Article

[Significance of the double mutations of C1673T/C1799G in HBV C promoter].

Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Oct 2012

Hu Zhang-Yong, Yang Jun, Xia Shao-Bi, Deng Lan, Wang Ya-Li, Fan Ling, Shi Han

Abstract excerpt

OBJECTIVE: To explore the biological and clinical significance of the double mutations of C1673T/C1799G in HBV C promoter (CP). METHODS: Totally 136 patients were enrolled, including 25 asymptomatic carriers (AsC), 38 patients with chronic hepatitis B (CHB), 24 patients with chronic severe hepatitis B (CSHB), 36 cases with liver cirrhosis (LC) and 13 cases with hepatocellular carcinoma (HCC). HBV subgenotypes and...

Topics

Adolescent
Adult
Aged
Female
Genotype
Hepatitis B e Antigens
Hepatitis B virus
Hepatitis B, Chronic
Humans
Male
Middle Aged
Mutation
Promoter Regions, Genetic

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Open in PubMed

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PMID: 23547448

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