Article
T cell recognition in chronic beryllium disease.
Clinical immunology (Orlando, Fla.) - 1 Nov 2006
Amicosante Massimo, Fontenot Andrew P
Abstract excerpt
Chronic beryllium disease (CBD) is a granulomatous lung disorder caused by beryllium exposure in the workplace and is characterized by the accumulation of beryllium-specific CD4(+) T cells. Depending on genetic susceptibility and the nature of the exposure, CBD occurs in up to 20% of exposed workers. Genetic susceptibility has been associated with particular HLA-DP alleles, especially those possessing a...
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