Article
A mutant mouse with severe anemia and skin abnormalities controlled by a new allele of the flaky skin (fsn) locus.
Experimental animals - 1 Jul 2005
Takabayashi Shuji, Katoh Hideki
Abstract excerpt
We found a novel recessive mutation in an inbred strain, INT, that was derived from an ICR closed colony. Mice homozygous for this mutation are identified by severe anemia, dysgenesis and neonatal death. This mutation was tentatively named int. Intercrosses of int heterozygotes (+/int) and the flaky skin heterozygotes (+/fsn) resulted in abnormal mice (int/fsn heterozygotes) showing anemia and flaky skin with the...
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