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Article

The peripheral lymphoid compartment is disrupted in flaky skin mice.

Immunology and cell biology - 1 Feb 2000

Abernethy N J, Hagan C, Tan P L, Birchall N M, Watson J D

Abstract excerpt

Flaky skin (fsn) is an autosomal recessive mutation on mouse chromosome 17 that causes severe anaemia, forestomach papillomatosis and a papulosquamous skin disease that resembles psoriasis in humans. In the present paper, it is reported that fsn causes peripheral lymphadenopathy, CD4/CD8 imbalance and hyperresponsiveness to T cell growth factors. Peripheral lymph nodes (PLN) of adult mutant (fsn/fsn) mice were...

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Source

Identifiers

PMID: 10651923
DOI: 10.1046/j.1440-1711.2000.00866.x

Genes

PLN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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