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Article

bfb, a novel ENU-induced blebs mutant resulting from a missense mutation in Fras1.

PloS one - 1 Jan 2013

Miller Kerry A, Gordon Christopher T, Welfare Megan F, Caruana Georgina, Bertram John F, Bateman John F, Farlie Peter G

Abstract excerpt

Fras1 is an extracellular matrix associated protein with essential roles in adhesion of epithelia and mesenchyme during early embryonic development. The adhesive function of Fras1 is achieved through interaction with a group of related proteins, Frem 1-3, and a cytoplasmic adaptor protein Grip1. Mutation of each of these proteins results in characteristic epithelial blistering and have therefore become known as...

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Identifiers

PMID: 24143185
DOI: 10.1371/journal.pone.0076342
PMCID: PMC3797057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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