Article
Spatially restricted hypopigmentation associated with an Ednrbs-modifying locus on mouse chromosome 10.
Genome research - 1 Jan 2000
Rhim H, Dunn K J, Aronzon A, Mac S, Cheng M, Lamoreux M L, Tilghman S M, Pavan W J
Abstract excerpt
We have used the varied expressivity of white spotting (hypopigmentation) observed in intrasubspecific crosses of Ednrb(s) mice (Mayer Ednrb(s)/Ednrb(s) and C3HeB/FeJ Ednrb(s)/Ednrb(s)) to analyze the effects of modifier loci on the patterning of hypopigmentation. We have confirmed that an Ednrb(s) modifier locus is present on mouse Chromosome 10. This locus is now termed k10, using the nomenclature established...
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