Article
Effects of Na+-Ca2+ exchange expression on excitation-contraction coupling in genetically modified mice.
Annals of the New York Academy of Sciences - 1 Jun 2005
Goldhaber Joshua I, Henderson Scott A, Reuter Hannes, Pott Christian, Philipson Kenneth D
Abstract excerpt
We have created genetically altered mice to investigate how expression of the Na(+)-Ca(2+) exchange protein alters excitation-contraction (E-C) coupling. Whereas low levels of exchanger overexpression have minimal effects on E-C coupling properties, high levels of overexpression in homozygous ani...
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