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Article

Hypertrophy and heart failure in mice overexpressing the cardiac sodium-calcium exchanger.

Journal of cardiac failure - 1 May 2007

Roos Kenneth P, Jordan Maria C, Fishbein Michael C, Ritter Matthew R, Friedlander Martin, Chang Helen C, Rahgozar Paymon, Han Tieyan, Garcia Alejandro J, Maclellan W Robb, Ross Robert S, Philipson Kenneth D

Abstract excerpt

BACKGROUND: The cardiac sodium-calcium exchanger (NCX1) is a key sarcolemmal protein for the maintenance of calcium homeostasis in the heart. Because heart failure is associated with increased expression of NCX1, heterozygous (HET) and homozygous (HOM) transgenic mice overexpressing NCX1 were dev...

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Identifiers

PMID: 17517353
DOI: 10.1016/j.cardfail.2007.01.004
PMCID: PMC2017112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17517353-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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