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Article

Gene transfer of troponin I isoforms, mutants, and chimeras.

Advances in experimental medicine and biology - 1 Jan 2003

Westfall Margaret V, Metzger Joseph M

Abstract excerpt

Thin filament proteins play an essential role in the regulation of myocardial pressure development. Within the thin filament of the sarcomere, troponin I (TnI) plays a key role in regulating the Ca(2+) sensitivity of force. During myocardial development, there is a transition in TnI isoform expression from the slow skeletal isoform (ssTnI) in embryonic/fetal myocardium to the cardiac isoform (cTnI) expressed in...

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PMID: 15098664
DOI: 10.1007/978-1-4419-9029-7_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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