Article
Planar signaling and morphogenesis in Drosophila.
Developmental cell - 1 May 2002
Adler Paul N
Abstract excerpt
The regulatory mechanisms governing the parallel alignment of hairs, bristles, and ommatidia in Drosophila have all served as model systems for studying planar signaling and tissue level morphogenesis. Polarity in all three systems is mediated by the serpentine receptor Frizzled and a number of additional gene products. The localized accumulation of these proteins within cells plays a key role in the development...
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