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Article

Directional non-cell autonomy and the transmission of polarity information by the frizzled gene of Drosophila.

Nature - 1 Jan 2000

Vinson C R, Adler P N

Abstract excerpt

The function of the frizzled (fz) locus is required for the development of a parallel array of bristles and hairs on the adult cuticle of Drosophila melanogaster. Marked fz mitotic clones from five alleles were generated and examined in the wing. Three alleles have a non-cell-autonomous hair polarity phenotype; wild-type cells distal to fz clones produce hairs that have an abnormal polarity. In contrast, fz...

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PMID: 3116434
DOI: 10.1038/329549a0

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