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Article

Directional non-cell autonomy and the transmission of polarity information by the frizzled gene of Drosophila.

Nature - 1 Jan 2000

Vinson C R, Adler P N

Abstract excerpt

The function of the frizzled (fz) locus is required for the development of a parallel array of bristles and hairs on the adult cuticle of Drosophila melanogaster. Marked fz mitotic clones from five alleles were generated and examined in the wing. Three alleles have a non-cell-autonomous hair polarity phenotype; wild-type cells distal to fz clones produce hairs that have an abnormal polarity. In contrast, fz...

Topics

Alleles
Animals
Clone Cells
Drosophila melanogaster
Eye
Genes
Hair
Morphogenesis
Mutation
Skin
Wings, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 3116434
DOI: 10.1038/329549a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3116434-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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