Article
Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics.
Genome research - 1 Aug 2005
Gertz Jason, Riles Linda, Turnbaugh Peter, Ho Su-Wen, Cohen Barak A
Abstract excerpt
Completing the annotation of a genome sequence requires identifying the regulatory sequences that control gene expression. To identify these sequences, we developed an algorithm that searches for short, conserved sequence motifs in the genomes of related species. The method is effective in findin...
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