Article
A novel mechanism for target gene-specific SWI/SNF recruitment via the Snf2p N-terminus.
Nucleic acids research - 1 May 2011
Weider M, Schröder A, Klebl F, Sauer N
Abstract excerpt
Chromatin-remodeling complexes regulate the expression of genes in all eukaryotic genomes. The SWI/SNF complex of Saccharomyces cerevisiae is recruited to its target promoters via interactions with selected transcription factors. Here, we show that the N-terminus of Snf2p, the chromatin remodeling core unit of the SWI/SNF complex, is essential for the expression of VHT1, the gene of the plasma membrane...
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