Article
DISC1 and neurocognitive function in schizophrenia.
Neuroreport - 22 Aug 2005
Burdick Katherine E, Hodgkinson Colin A, Szeszko Philip R, Lencz Todd, Ekholm Jenny M, Kane John M, Goldman David, Malhotra Anil K
Abstract excerpt
We recently reported an association between DISC1 and schizophrenia, schizoaffective disorder, and bipolar disorder. Convergent evidence suggests that DISC1 has a direct effect on central nervous system functioning. However, there is a paucity of data investigating the effects of DISC1 on neurocognition. Thus, we analyzed the relationship between five single-nucleotide polymorphisms that influenced risk for...
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