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Article

Rybp/DEDAF is required for early postimplantation and for central nervous system development.

Molecular and cellular biology - 1 Aug 2005

Pirity Melinda K, Locker Joseph, Schreiber-Agus Nicole

Abstract excerpt

The Rybp/DEDAF protein has been implicated in both transcriptional regulation and apoptotic signaling, but its precise molecular function is unclear. To determine the physiological role of Rybp, we analyzed its expression during mouse development and generated mice carrying a targeted deletion of Rybp using homologous recombination in embryonic stem cells. Rybp was found to be broadly expressed during...

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Identifiers

PMID: 16055728
DOI: 10.1128/MCB.25.16.7193-7202.2005
PMCID: PMC1190233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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