Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Yaf2 inhibits caspase 8-mediated apoptosis and regulates cell survival during zebrafish embryogenesis.

The Journal of biological chemistry - 29 Sept 2006

Stanton Sasha E, McReynolds Lisa J, Evans Todd, Schreiber-Agus Nicole

Abstract excerpt

Rybp (DEDAF) is a member of the Rybp/Yaf2 protein family and has been shown to encode pro-apoptotic functions and to be essential for mouse embryogenesis. The related Yaf2 protein has not been studied extensively at the cellular or organismal levels. Here we describe zebrafish yaf2 (zyaf2) and show that it is widely expressed during early embryogenesis, with subsequent enrichment of transcripts in the anterior...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caspase 8

Share to Cell Survival

Share to Gene Expression Regulation, Developmental

Share to In Situ Hybridization

Share to Zebrafish

Share to Zebrafish Proteins

Source

Identifiers

PMID: 16891308
DOI: 10.1074/jbc.M603348200

Genes

YAF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yaf2 inhibits caspase 8-mediated apoptosis and regulates cell survival during zebrafish embryogenesis.PMID 16891308Read ↗

Rybp/DEDAF is required for early postimplantation and for central nervous system development.Semantic proximity Read ↗

Apaf1 apoptotic function critically limits Sonic hedgehog signaling during craniofacial development.Semantic proximity Read ↗

Xeya3 regulates survival and proliferation of neural progenitor cells within the anterior neural plate of Xenopus embryos.Semantic proximity Read ↗

The Drosophila CPEB protein Orb2 has a novel expression pattern and is important for asymmetric cell division and nervous system function.Semantic proximity Read ↗

Mutations affecting neural survival in the zebrafish Danio rerio.Semantic proximity Read ↗

Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain.Semantic proximity Read ↗

Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosisSemantic proximity Read ↗

Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic responseSemantic proximity Read ↗

Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic responseSemantic proximity Read ↗

Zebrafish pax8 is required for otic placode induction and plays a redundant role with Pax2 genes in the maintenance of the otic placode.Semantic proximity Read ↗

Misexpression of the eyes absent family triggers the apoptotic program.Semantic proximity Read ↗

Pax2/Pax8-defined subdomains and the occurrence of apoptosis in the posterior placodal area of mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.