Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional interactions between the Moses corepressor and DHR78 nuclear receptor regulate growth in Drosophila.

Genes & development - 15 Feb 2007

Baker Keith D, Beckstead Robert B, Mangelsdorf David J, Thummel Carl S

Abstract excerpt

Expression of the Drosophila orphan nuclear receptor DHR78 is regulated by the steroid hormone ecdysone and is required for growth and viability during larval stages. In contrast to our understanding of its biological functions, however, relatively little is known about how DHR78 acts as a transcription factor. Here we show that DHR78 is an obligate partner for Moses (Middleman of seventy-eight signaling), a SAM...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila melanogaster
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Lethal

Share to In Situ Hybridization

Share to Neoplasms

Share to Protein Structure, Tertiary

Share to Receptors, Cytoplasmic and Nuclear

Share to Repressor Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 17322404
DOI: 10.1101/gad.1519007
PMCID: PMC1804333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional interactions between the Moses corepressor and DHR78 nuclear receptor regulate growth in Drosophila.PMID 17322404Read ↗

SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development.Semantic proximity Read ↗

The DHR78 nuclear receptor is required for ecdysteroid signaling during the onset of Drosophila metamorphosis.Semantic proximity Read ↗

Sex- and tissue-specific functions of Drosophila doublesex transcription factor target genes.Semantic proximity Read ↗

The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster.Semantic proximity Read ↗

Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila.Semantic proximity Read ↗

Genetic control of specificity to steroid-triggered responses in Drosophila.Semantic proximity Read ↗

Drosophila hormone receptor 38 functions in metamorphosis: a role in adult cuticle formation.Semantic proximity Read ↗

Drosophila DHR38 nuclear receptor is required for adult cuticle integrity at eclosion.Semantic proximity Read ↗

Nuclear receptor E75/NR1D2 drives tumor malignant transformation by integrating Hippo and Notch pathwaysSemantic proximity Read ↗

CDK8-Cyclin C Mediates Nutritional Regulation of Developmental Transitions through the Ecdysone Receptor in Drosophila.Semantic proximity Read ↗

A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP.Semantic proximity Read ↗

The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.