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Article

The Drosophila SET domain encoding gene dEset is essential for proper development.

Hereditas - 1 Dec 2006

Stabell Marianne, Bjørkmo Mona, Aalen Reidunn B, Lambertsson Andrew

Abstract excerpt

We have identified dEset, the fly homolog of human SETDB1 and mouse ESET histone lysine methyltransferases (HKMTases) that methylates the lysine 9 residue of histone 3 (H3-K9) and negatively regulates transcription of target genes. By using spatio-temporal RNA interference we show that dEset is required at several stages of development coinciding with ecdysone pulses, possibly as a repressor of transcription of...

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Source

Identifiers

PMID: 17362353
DOI: 10.1111/j.2006.0018-0661.01970.x

Genes

SET
SETDB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Drosophila SET domain encoding gene dEset is essential for proper development.PMID 17362353Read ↗

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