Article
Effect of genetic variants of chemokine receptors on the development of myocardial infarction in Turkish population.
Molecular biology reports - 1 Oct 2010
Karaali Zeynep Ermis, Sozen Seyma, Yurdum Melis, Cacina Canan, Toptas Bahar, Gok Ozlem, Agachan Bedia
Abstract excerpt
Inflammation is a crucial component of coronary atherosclerosis and myocardial infarction (MI). Chemokine receptors are important modulators of inflammation. Polymorphisms in genes coding for chemokine receptors, CCR2 and CCR5, have been studied as genetic markers of coronary artery disease. In the present study, we investigated whether genetic variants of CCR2-V64I and CCR5-delta32 chemokine receptors have any...
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