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Article

Association between genotype at an exonic SNP in DISC1 and normal cognitive aging.

Neuroscience letters - 25 Nov 2005

Thomson P A, Harris S E, Starr J M, Whalley L J, Porteous D J, Deary I J

Abstract excerpt

DISC1 is expressed in the hippocampus and has been identified as a possible genetic risk factor for both schizophrenia and bipolar disorder. These psychiatric illnesses are associated with impaired learning and memory. This study investigates the association of variation in DISC1 with cognitive function on the same general mental ability test (Moray House Test) at age 11 and age 79, and cognitive change between...

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Source

Identifiers

PMID: 16054297
DOI: 10.1016/j.neulet.2005.07.004

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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