Article
DTNBP1 genotype influences cognitive decline in schizophrenia.
Schizophrenia research - 1 Jan 2007
Burdick Katherine E, Goldberg Terry E, Funke Birgit, Bates John A, Lencz Todd, Kucherlapati Raju, Malhotra Anil K
Abstract excerpt
OBJECTIVE: Intellectual decline is common in schizophrenia and predicts functional outcome. While many patients undergo intellectual decline that typically predates the onset of symptoms, few studies have investigated the underlying mechanism through which this occurs. The current study assessed the relationship between intellectual decline in schizophrenia and genetic variation in dysbindin-1 (DTNBP1). METHODS:...
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