Article
Genetic variation influences the risk of bleeding after cardiac surgery: novel associations and validation of previous findings.
Acta anaesthesiologica Scandinavica - 1 Jul 2015
Greiff G, Pleym H, Stenseth R, Wahba A, Videm V
Abstract excerpt
BACKGROUND: Severe post-operative bleeding in cardiac surgery is associated with increased morbidity and mortality. We hypothesized that variation in genetic susceptibility contributes to post-operative bleeding in addition to clinical factors. METHODS: We included 1036 adults undergoing cardiac surgery with cardiopulmonary bypass. Two different endpoints for excessive post-operative bleeding were used, either...
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