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Article

249ser p53 mutation in the serum of black southern African patients with hepatocellular carcinoma.

Journal of gastroenterology and hepatology - 1 Aug 2005

Kimbi Gerald C, Kew Michael C, Yu Mimi C, Arakawa Kazuko, Hodkinson John

Abstract excerpt

BACKGROUND AND AIMS: A specific mutation at codon 249 of the p53 tumor suppressor gene (guanine to thymine; arginine to serine [249(serine)p53]) is present in the cell-free plasma of 30-47% of patients with hepatocellular carcinoma (HCC) in regions with uniformly high levels of dietary exposure to the fungal toxin, aflatoxin B(1). No information is available from other regions. We therefore examined cell-free...

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Identifiers

PMID: 16048565
DOI: 10.1111/j.1440-1746.2005.03951.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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