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Article

Ser-249TP53 mutation in tumour and plasma DNA of hepatocellular carcinoma patients from a high incidence area in the Gambia, West Africa.

International journal of cancer - 20 Jun 2004

Szymańska Katarzyna, Lesi Olufunmilayo A, Kirk Gregory D, Sam Omar, Taniere Philippe, Scoazec Jean-Yves, Mendy Maimuna, Friesen Marlin D, Whittle Hilton, Montesano Ruggero, Hainaut Pierre

Abstract excerpt

Hepatocellular carcinoma (HCC) is frequent in areas of high exposure to aflatoxin and high prevalence of HBV infection, such as western Africa and south-east China. A selective mutation in TP53 (AGG-->AGT at codon 249, Arg-->Ser) has been identified as a hotspot in HCCs from such areas, reflectin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Carcinoma, Hepatocellular

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Source

Identifiers

PMID: 15095302
DOI: 10.1002/ijc.20103

Genes

AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15095302-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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