Article
Pleiotropic QTL on chromosome 19q13 for triglycerides and adiposity: the HERITAGE Family Study.
Atherosclerosis - 1 Apr 2006
Feitosa Mary F, Rice Treva, North Kari E, Kraja Aldi, Rankinen Tuomo, Leon Arthur S, Skinner James S, Blangero John, Bouchard Claude, Rao D C
Abstract excerpt
Motivated by strong correlations between plasma levels of triglycerides (TG) and adiposity traits, we conducted a series of bivariate genome-wide linkage analyses of TG with body mass index (BMI), total fat mass (FAT), percentage of body fat (FATPC), and abdominal subcutaneous fat (ASF). Maximum lod scores of 3.3, 3.0, 2.2 and 2.4, respectively, were found on chromosome 19q13. This linkage region includes the...
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