Article
Genome scan for human obesity and linkage to markers in 20q13.
American journal of human genetics - 1 Jan 1999
Lee J H, Reed D R, Li W D, Xu W, Joo E J, Kilker R L, Nanthakumar E, North M, Sakul H, Bell C, Price R A
Abstract excerpt
Obesity is a highly prevalent, multigenic trait that predicts increased morbidity and mortality. Here we report results from a genome scan based on 354 markers in 513 members of 92 nuclear families ascertained through extreme obesity and normal body weight. The average marker interval was approximately 10 cM. We examined four correlated obesity phenotypes, including the body-mass index (BMI) (both as a...
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