Plasma HDL cholesterol, triglycerides, and adiposity. A quantitative genetic test of the conjoint trait hypothesis in the San Antonio Family Heart Study.

doi:10.1161/01.cir.92.11.3240

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Article

Plasma HDL cholesterol, triglycerides, and adiposity. A quantitative genetic test of the conjoint trait hypothesis in the San Antonio Family Heart Study.

Circulation - 1 Dec 1995

Mahaney M C, Blangero J, Comuzzie A G, VandeBerg J L, Stern M P, MacCluer J W

Abstract excerpt

BACKGROUND: The conjoint trait hypothesis proposes that combined low HDL cholesterol (HDL-C) and high triglyceride (TG) levels represent a single, inherited phenotype that adiposity may influence in an unspecified manner. We conducted formal statistical genetic tests of the conjoint trait hypothesis and the relation of the conjoint trait to adiposity using data for 569 subjects in 25 pedigrees from the San...

Topics

Adipose Tissue
Adolescent
Adult
Aged
Aged, 80 and over
Arteriosclerosis
Body Mass Index
Cholesterol, HDL
Female
Genetic Variation
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Likelihood Functions

Male

Mexican Americans

Middle Aged

Multivariate Analysis

Obesity

Pedigree

Source

Open in PubMed

Identifiers

PMID: 7586310
DOI: 10.1161/01.cir.92.11.3240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7586310-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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